For general inquiries, call 1 877-564-0008 or [email protected]. Fax PoNS device prescriptions to 1 (215) 754-4903.

The Results Are In: PoNS Therapy® Makes a Real, Sustained Difference For People with MS

Living with MS often means adapting to changes in how your body moves—and for many, that includes challenges with walking. Whether it’s unsteadiness, slower movement, or the fear of falling, gait issues can take a serious toll on your daily life.

That’s why the recent release of full data from the PoNSTEP Study is such good news.

This real-world study looked at how people with mild-to-moderate MS responded to PoNS Therapy®—a 14-week program that combines physical rehabilitation with gentle, non-invasive electrical stimulation through a small device worn on the tongue, with the aim of improving the patient’s gait.

And the results? They show real, measurable progress.

A 14-Week Journey Back Into Motion

PoNS Therapy® isn’t just a device—it’s a program built on partnership, consistency, and the power of neuroplasticity. The full 14-week PoNS treatment protocol is designed to help patients retrain their brain to improve their walking ability, through consistent physical therapy paired with our neuroplasticity-inducing PoNS device. Like any great journey, success with PoNS starts with commitment and consistency. Patients who stick with the full 14-week program—as guided by their PoNS trainer—can experience meaningful changes in mobility and confidence.

What the PoNSTEP Study Found

Researchers followed 43 people with MS who were dealing with walking and balance difficulties. All participants used the PoNS® Here’s what they found:
  • 74% of people who maintained a minimum of ≥70% adherence to the program improved their Dynamic Gait Index (DGI) scores by 4 points or more
  • 50% of those who followed the program 85–100% of the time improved by nearly 7 points — a major gain in walking ability
  • Even more encouraging: these improvements in walking ability were still present 6 months after the program ended

These numbers aren’t just impressive—they’re meaningful. Even just a few points of progress on the DGI can lead to fewer falls, less reliance on walking aids, and more confidence in your day-to-day movement.

Why It Works: The Power of Neuroplasticity

PoNS Therapy works by tapping into something called neuroplasticity—your brain’s ability to adapt and build new connections. When combined with targeted physical therapy, the gentle stimulation from the PoNS® device helps “retrain” the brain to improve movement, coordination, and stability. Think of it as giving your brain a helpful nudge during rehab — so it learns more effectively, and the improvements last longer.

Individual results and experiences may vary. Talk to your doctor to see if PoNS is right for you.

Ready to Take the Next Step?

If you’re living with MS and feeling stuck with mobility issues, this new data offers something important:
hope backed by evidence.

With the right support—and a strong commitment to the program—many patients are seeing real, sustained improvements in their movement abilities, helping them to Get Back In Step With Life.

If you’re ready to take your own first steps with PoNS, talk to your healthcare provider about whether PoNS Therapy® could be right for you. Because when it comes to your mobility, every step forward matters.

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IMPORTANT SAFETY INFORMATION

No serious adverse events related to the PoNS device were reported in the MS RCTs or in use in clinical rehabilitation settings to treat balance and gait disorders.

Some individuals have reported headaches, fatigue, and excess salivation. Excess salivation during training sessions often occurs but generally improves as patients get used to wearing the mouthpiece.

Indication
The PoNS® device is indicated for use as a short term treatment of gait deficit due to mild to moderate symptoms from multiple sclerosis and is to be used as an adjunct to a supervised therapeutic exercise program for adults 22 years of age and over by prescription only.

Contraindications
The PoNS® device delivers electrical stimulation directly to the surface of the tongue. Precautions for use are similar to those for transcutaneous electrical nerve stimulation (TENS).

Electrical stimulation should not be used:

  • If there is an active or suspected malignant tumor
  • In areas of recent bleeding or open wounds
  • In areas that lack normal sensation

The PoNS® has not been tested on, and thus should not be used by individuals who are pregnant. Do not use the PoNS® if you are sensitive to nickel, gold or copper.

Use with caution
Electrical stimulation should only be used after seeking professional medical advice, and with caution in patients with any of the following:

  • Implanted electronic devices, including:
    • Cardiac pacemakers
    • Cardioverter defibrillators
    • Deep Brain Stimulators
    • Vagal Nerve Stimulators
    • Sacral nerve stimulators
    • Cochlear Implants
  • Metal in the mouth (e.g. piercings, braces, retainers, or other orthodontic appliance)
  • Seizure disorders
  • Epilepsy

Ready to get started with PoNS?

Patients who are seeking more information on how to get PoNS can email us at [email protected], or fill out our contact form: